Speakers - 2026

Title: Safety and efficacy of resistance training in patients with spinal metastases: a systematic review and meta-analysis

Abstract

Spinal metastases occur in up to 70% of patients with cancer. Traditionally, physical activity in this population has been restricted due to concerns about skeletal complications. However, in recent years, supervised exercise interventions have demonstrated potential benefits.

The aim of this systematic review was to evaluate the safety and efficacy of resistance training in patients with spinal metastasis. A systematic search of seven databases (PubMed, MEDLINE, Embase, Cochrane, CNKI, Airiti Library, ClinicalTrials.gov) was performed from their inception dates to March 9, 2026. Randomized trials were included for meta-analysis.

A total of seven studies involving 471 participants were included. Compared to control group, experimental group had lower risk of pathological fractures (OR = 0.24; 95% CI = 0.14 - 0.43). Though, no significant difference were in bone density (MD = 4.59, 95% CI = -39.91 - 49.09), pain scale (SMD = - 0.61; 95% CI = - 2.10 - 0.88), and quality of life (MD = - 0.61; 95% CI = - 2.10 - 0.88), the result showed an upward trend in the experimental group.

What will the audience take away from presentation?

Explain how the audience will be able to use what they learn?

• Resistance training can be safely implemented in patients with spinal (vertebral) metastases under appropriate supervision.
• Exercise interventions may reduce the risk of pathological fractures in this population.
• This research provides evidence to support a shift away from overly restrictive activity recommendations.

How will this help the audience in their job? Is this research that other faculty could use to expand their research or teaching? Does this provide a practical solution to a problem that could simplify or make a designer’s job more efficient? Will it improve the accuracy of a design, or provide new information to assist in a design problem? List all other benefits.  When we concern about the quality of life for patients of advanced cancer and their care-giver, rehabilitation could help their life well.

• Audience members, especially clinicians and rehabilitation specialists, can apply these findings by integrating safe, supervised resistance training into care plans for patients with spinal metastases.
• This study provides practical, evidence-based guidance for improving the quality of life of patients with advanced cancer.